Microbiological characteristics of neonatal sepsis

Abstract

Neonatal sepsis is a clinical syndrome characterized by systemic signs of infection, caused by the invasion of pathogens into the bloodstream. Isolation of bacteria by blood culture is the gold standard to confirm your diagnosis. The diagnosis must be early and the treatment must be started before having blood culture results based on the most common microorganisms in the locality. The National Hospital of Chiquimula does not always have the resource to carry out blood culture to patients, so the microbiological profile and local resistance patterns are unknown, so it was decided to carry out a cross-sectional descriptive study in the months of June and July 2018 in order to determine the microbiological characteristics of neonatal sepsis its pattern of sensitivity and antimicrobial resistance, taking into account 80 patients diagnosed with neonatal sepsis or suspected neonatal sepsis who underwent a blood culture before starting antibiotic treatment . The diagnosis of the patients was made based on the maternal history and the haematological alterations of the patient. The 80 blood cultures were negative at seven days of incubation, so it was not possible to know the microorganisms causing neonatal sepsis, sensitivity and antimicrobial resistance, however improvement was observed in 81% of the patients with the empirical antibiotic treatment used, it was verified that the empirical treatment used in the National Hospital of Chiquimula continues to be effective in patients with neonatal sepsis.