D-Dimer in infectious diseases not associated to COVID-19

Authors

DOI:

https://doi.org/10.36314/cunori.v8i2.264

Keywords:

D-dimer, Covid-19

Abstract

OBJECTIVE: Describe the elevation of D-dimer with infectious diseases not associated with COVID-19. METHOD: Retrospective descriptive study of 54 patients admitted to the Pediatrics Department of the Zacapa Regional Hospital from March 2020 to February 2024. RESULTS: The most frequent disease and elevation of D-dimer was community-associated pneumonia (30%), the most affected age group was the neonatal age (31%), the most frequent gender was female (56%), it was determined that the range present in the clinical records with elevated D-dimer were negative values ​​​​from 0 to 500 ng / mL (35%), 2000 to 5000 ng / mL (24%) and ≥ 5000 ng / mL (17%), there were 8 cases of death in total out of 54 records, which represented mortality of 15%, and a hospital stay ≥ 10 days in 61%. CONCLUSION: Regarding the study, elevated D-dimer could be observed in patients with infectious diseases not associated with COVID-19 since 65% had elevated values ​​​​compared to 35% who remained negative.

Downloads

Download data is not yet available.

Author Biography

Silvia María Rivera Andrade, Universidad de San Carlos de Guatemala

Es egresada de la Carrera de Médico y Cirujano del Centro Universitario de Oriente de la Universidad de San Carlos de Guatemala. Es autora de la tesis presentada como trabajo de graduación titulado “Dímero D en enfermedades Infecciosas no Asociadas a COVID-19

References

Cerquera Rojas, J. F. y Losada Gómez, C. L. (2012). Utilidad del dímero D en la evaluación de la fibrinólisis por dengue en la población pediátrica del departamento de Huila, Colombia [tesis de maestría, Universidad Sur Colombiana]. Contenidos USCO.

https://contenidos.usco.edu.co/salud/images/documentos/grados/T.G.Pediatria/24. T.G-Jhon-Ferney-Cerquera-Rojas-Claudia-Liliana-Losada-Gmez-2012.pdf

El-Shahat, N. H., El Shiekh, A. R., Alaa, Z. M., & Elgebaly, S. M. (2022). Study of diagnostic value of D-dimer serum level as a marker in neonatal sepsis. Egyptian Journal of Hospital Medicine, 86(1), 627–633. https://doi.org/10.21608/ejhm.2022.215200 DOI: https://doi.org/10.21608/ejhm.2022.215200

Esteghamati, M., Ghasemi, K., Javaheri, Z. y Zoghi, G. (2021). Plasma D-dimer as a marker of urinary tract infection in children. Nephro-urology monthly, 13(Issue 4), e117054. https://doi.org/10.5812/numonthly.117054 DOI: https://doi.org/10.5812/numonthly.117054

Favresse, J., Lippi, G., Roy, P.-M., Chatelain, B., Jacqmin, H., Ten Cate, H. y Mullier, F. (2018). D-dimer: Preanalytical, analytical, postanalytical variables, and clinical applications. Critical Reviews in Clinical Laboratory Sciences, 55(Issue 8), 548–577.

https://doi.org/10.1080/10408363.2018.1529734 DOI: https://doi.org/10.1080/10408363.2018.1529734

Gil Sanchez, J. A., Osona Rodríguez de Torres B., Peña Zarza, J. A., Celorio Duarte, S., Beltrán Arasa, E. y Figueroa Mulet, J. (6-8 de mayo de 2010). Biomarcadores de fibrinolisis y relación con la gravedad de las neumonías adquiridas en la comunidad. En XXXII Reunión de la Sociedad Española de Neumología Pediátrica. Anales de Pediatría, 72(Espec. Cong. 1), 76. DOI: https://doi.org/10.1016/j.anpedi.2009.06.004

https://www.analesdepediatria.org/index.php?p=revista&tipo=pdf-simple&pii=X1695403310502026.

Linkins, L.-A., y Takach Lapner, S. (2017). Review of D-dimer testing: good, bad, and ugly. International Journal of Laboratory Hematology, 39(Suppl. 1), 98–103. https://onlinelibrary.wiley.com/doi/epdf/10.1111/ijlh.12665 DOI: https://doi.org/10.1111/ijlh.12665

Nso Roca, A. P., Riesco Riesco, S., Benito Gutiérrez, M. y García Aparicio, J. (2009).

Utilidad del dímero D como marcador analítico en urgencias pediátricas. Revista de la Sociedad Española de Medicina de Urgencias y Emergencias, 21(1), 28-31. https://dialnet.unirioja.es/servlet/articulo?codigo=2865003

Sheng, C.-Q., Yang, C.-F., Ao, Y., Zhao, Z.-Y. y Li, Y.-M. (2021). Mycoplasma pneumoniae pneumonia with pulmonary embolism: a study on pediatric cases in Jilin province of China. Experimental and Therapeutic Medicine, 21(Issue 3). https://doi.org/10.3892/etm.2021.9634 DOI: https://doi.org/10.3892/etm.2021.9634

Shobhavat, L., Solomon, R., Rao, S., Bhagat, I., Prabhu, S., Prabhu, S., Chandrakar, M. y Bodhanwala, M. (2020). Multisystem Inflammatory Syndrome in children: Clinical Features and management-Intensive Care Experience from a Pediatric Public Hospital in Western India. Indian Journal of Critical Care Medicine, 24(Issue 11), 1089–1094. https://doi.org/10.5005/jp-journals-10071-23658. DOI: https://doi.org/10.5005/jp-journals-10071-23658

Villa Chavarría, J. A. (2020). Dímero - D como marcador serológico en pacientes con artritis séptica [tesis de maestría, Universidad Autónoma de Nuevo León]. Repositorio Académico Digital UANL. http://eprints.uanl.mx/21903/1/21903.pdf

Published

2024-08-15

How to Cite

Rivera Andrade, S. M. (2024). D-Dimer in infectious diseases not associated to COVID-19. Revista Ciencia Multidisciplinaria CUNORI, 8(2), 1–14. https://doi.org/10.36314/cunori.v8i2.264

Issue

Section

Artículos científicos